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The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
A role for tonsillectomy in the treatment of psoriasis?
B D McMillin1, B R Maddern, W R Graham
1Division of Otolaryngology, Nemours Children's Clinic, Jacksonville, Fla. 32207, USA. dmcmillin@nemours.org
Insights
Tonsillectomy may benefit children with recurrent guttate psoriasis linked to streptococcal infections. Surgical removal of tonsils led to significant psoriasis improvement and long-term remission in a small case study.
Area of Science:
- Dermatology
- Otolaryngology
- Pediatrics
Background:
- Recurrent guttate psoriasis in children can be debilitating.
- Association between streptococcal pharyngotonsillitis and psoriasis exacerbations is recognized.
- Limited evidence exists on surgical interventions for this specific condition.
Observation:
- Two pediatric cases with recurrent guttate psoriasis and streptococcal pharyngotonsillitis were reviewed.
- Both patients underwent adenotonsillectomy as a treatment intervention.
- Psoriasis severity and frequency of outbreaks were monitored post-surgery.
Findings:
- Both patients demonstrated significant improvement in guttate psoriasis following adenotonsillectomy.
- Complete remission of psoriatic lesions was observed in both children at 16-month follow-up.
- No psoriatic relapses were reported during the follow-up period.
Implications:
- Adenotonsillectomy may be a beneficial treatment option for children with recurrent guttate psoriasis and recurrent streptococcal pharyngotonsillitis.
- This finding suggests a potential link between tonsillar infections and psoriasis pathogenesis in pediatric cases.
- Further prospective studies are warranted to validate these preliminary observations and establish treatment guidelines.
Abstract:
Our objective was to determine whether tonsillectomy is beneficial in the treatment of recurrent childhood guttate psoriasis that is associated with recurrent streptococcal pharyngitis and tonsillitis. We retrospectively reviewed the cases of two children who were referred to our facility for treatment of repeated exacerbations of psoriasis and recurrent streptococcal pharyngotonsillitis. Both patients experienced a significant improvement in their psoriasis after undergoing adenotonsillectomy, and both were completely free of psoriatic outbreaks after 16 months of follow-up. We conclude that tonsillectomy appears to be of benefit in the treatment of children with recurrent guttate psoriasis and recurrent streptococcal pharyngotonsillitis, and we hope that further investigation will be undertaken.
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