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Related Experiment Videos

Implantable electrode lead in a growing limb.

J M Akers1, B T Smith, R R Betz

  • 1Research Department, Shriners Hospitals for Children, Philadelphia, PA 19140, USA.

IEEE Transactions on Rehabilitation Engineering : a Publication of the IEEE Engineering in Medicine and Biology Society
|April 3, 1999
PubMed
Summary

This study shows that implantable electrode leadwires for spinal cord injury (SCI) patients can accommodate limb growth. Excess lead wire placed in subcutaneous tissue unwinds, maintaining electrode position and function during growth.

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Area of Science:

  • Biomedical Engineering
  • Neuroscience
  • Regenerative Medicine

Background:

  • Spinal cord injuries (SCI) often result in loss of limb function.
  • Implantable electrode systems offer a potential solution for restoring limb function.
  • Evaluating device performance during growth is crucial for pediatric or young patients.

Purpose of the Study:

  • To assess the long-term performance of an implantable electrode leadwire system in a growing animal model.
  • To determine if the system can maintain functionality and position despite limb growth.
  • To compare the efficacy of different lead management techniques for accommodating growth.

Main Methods:

  • Thirty implantable electrodes (epimysial and intramuscular) were implanted in young dogs' forelimb muscles.

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  • Excess lead wire was placed subcutaneously, some in protective pouches, others freely.
  • Motor responses (threshold, usable force range) were measured before and after growth, compared to new implants.

    • Main Results:

    • No significant difference was found in the usable force range of electrodes before and after growth.
    • A small, clinically insignificant increase in threshold was observed after growth.
    • Freely placed excess lead unwound effectively, rendering pouch enclosures unnecessary.
    • Most electrodes maintained position and function, with minimal lead tension observed.

    Conclusions:

    • The implantable electrode leadwire system demonstrates stable performance and position maintenance during limb growth.
    • Subcutaneous placement of excess lead wire is effective for accommodating growth in this system.
    • The findings support the potential of this technology for pediatric SCI patients requiring functional restoration.