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[Epilepsy with centrotemporal (Rolandic) spikes. A peculiar seizure disorder of childhood]

M Kriz, M Gazdik

    Neurologia I Neurochirurgia Polska
    |July 1, 1978
    PubMed

    Insights

    Rolandic epilepsy, a common childhood condition, often resolves favorably with treatment. Most children experience seizure freedom and normal EEGs after therapy, indicating a positive long-term outlook.

    Area of Science:

    • Pediatric Neurology
    • Epileptology
    • Clinical Neurophysiology

    Context:

    • Rolandic epilepsy (RE) is a frequent focal epilepsy syndrome in children.
    • Characterized by centrotemporal spikes on electroencephalogram (EEG).
    • Understanding its clinical course and treatment outcomes is crucial for pediatric care.

    Purpose:

    • To investigate the long-term clinical and EEG evolution of Rolandic epilepsy in a cohort of children.
    • To assess the efficacy of antiepileptic therapy in managing seizures and achieving remission.
    • To determine the natural history of EEG abnormalities in Rolandic epilepsy.

    Summary:

    • The study followed 60 children diagnosed with Rolandic epilepsy.
    • Rolandic epilepsy constitutes 13.4% of childhood epilepsy cases, peaking between ages 7-8.
    • Clinical presentations included generalized (60%) and partial seizures (40%).
    • Over 50% achieved seizure freedom with antiepileptic drugs, with 75% considered practically cured after 5 years seizure-free.
    • EEG spikes resolved in over 80% of cases within three years.

    Impact:

    • Provides evidence for the generally favorable prognosis of Rolandic epilepsy.
    • Highlights the effectiveness of antiepileptic therapy in achieving long-term remission.
    • Demonstrates the resolution of EEG abnormalities, suggesting neurophysiological recovery.

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