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Updated: Aug 15, 2026
13:33
Infinium Assay for Large-scale SNP Genotyping Applications
Published on: November 19, 2013
Powerful tools for genetic analysis come of age
1Department of Chemical Engineering, University of Pennsylvania, Philadelphia 19104-6393, USA.
Trends in Biotechnology
|April 6, 1999
Summary
Microscopic arrays, or microarrays, enable rapid, parallel measurement of gene expression and identification of genetic variations. This technology is revolutionizing genomic research and discovery.
Area of Science:
- Genomics
- Molecular Biology
- Biotechnology
Background:
- Microscopic arrays of oligonucleotides and cDNA are advanced tools in biological research.
- These arrays contain hundreds of thousands of unique sequences.
Purpose of the Study:
- To discuss the principles behind microarray technology.
- To highlight the impact of microarrays on genomic research methodologies.
- To identify current challenges and areas for future study in the field.
Main Methods:
- Utilizing microscopic arrays for high-throughput analysis.
- Employing parallel processing for genetic analysis.
- Measuring gene expression levels across numerous samples simultaneously.
Main Results:
- Enabled detection of gene polymorphisms and mutations with high speed.
- Facilitated measurement of gene expression with unprecedented parallelism.
- Influenced new methodologies and discovery pathways in genomics.
Conclusions:
- Microarray technology offers powerful capabilities for genomic research.
- Further research is needed to address existing challenges and optimize applications.
- This technology is transforming the speed and scope of genetic discovery.
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