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Antimicrobial selection, administration and dosage
1Preclinical Veterinary Studies, University of Zimbabwe, Harare, Zimbabwe.
Journal of the South African Veterinary Association
|April 7, 1999
Summary
Selecting the right antimicrobial drug for animals involves diagnosing the infection, identifying the pathogen, and considering drug properties and animal health. Dosage and duration depend on clinical response and bacterial culture, ensuring effective treatment.
Area of Science:
- Veterinary Medicine
- Pharmacology
- Microbiology
Background:
- Antimicrobial selection in animals requires integrating clinical, microbiological, and pharmacological data.
- Effective treatment necessitates a thorough understanding of infection characteristics and animal health status.
Purpose of the Study:
- To outline a comprehensive approach for selecting appropriate antimicrobial agents in veterinary medicine.
- To emphasize the importance of considering various factors for optimal therapeutic outcomes.
Main Methods:
- Diagnosis of infection site, nature, and severity.
- Identification of causative microorganisms and their antimicrobial susceptibility.
- Evaluation of drug pharmacokinetics, toxicity, and species-specific considerations.
Main Results:
- Clinical experience, microbiological data, and pharmacological properties guide antimicrobial selection.
- Dosage adjustments are necessary for animals with renal or hepatic impairment.
- Therapeutic success is determined by clinical assessment and bacterial culture monitoring.
Conclusions:
- A multi-faceted approach integrating clinical, microbiological, and pharmacological data ensures rational antimicrobial drug selection in animals.
- Monitoring treatment response is crucial for determining therapy duration and confirming successful outcomes.