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Primary esophageal T cell lymphoma.
S Fujisawa1, S Motomura, K Fujimaki
1First Department of Internal Medicine, Urafune Hospital, Yokohama City University School of Medicine, Kanagawa, Japan.
Leukemia & Lymphoma
|April 8, 1999
Summary
This case study presents a rare esophageal T-cell lymphoma successfully treated with irradiation. The patient experienced symptom resolution and achieved remission, highlighting effective therapeutic options for this uncommon malignancy.
Area of Science:
- Oncology
- Gastroenterology
- Hematology
Background:
- Primary esophageal lymphoma is an exceptionally rare condition.
- T-cell lymphoma of the esophagus is particularly uncommon, with limited reported cases.
- This report details a specific instance of esophageal T-cell lymphoma.
Observation:
- A 60-year-old female patient presented with clinical stage I(E)B esophageal T-cell lymphoma.
- Immunohistology confirmed T-cell lineage, with positive markers for LCA, UCHL-1, MT-1, and CD3, and negative for L26.
- The patient experienced dysphagia, a common symptom of esophageal disease.
Findings:
- Treatment with 65 Gy of irradiation led to complete resolution of dysphagia.
- Esophageal findings significantly improved post-irradiation.
- Subsequent esophageal biopsies confirmed the absence of malignancy, indicating successful treatment.
Implications:
- This case adds to the scarce literature on primary esophageal T-cell lymphoma.
- Radiation therapy appears to be an effective treatment modality for this rare esophageal malignancy.
- Further research into T-cell lymphoma of the esophagus is warranted due to its rarity.