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Updated: Jul 16, 2026

A Rodent Model of The Ross Operation: Syngeneic Pulmonary Artery Graft Implantation in A Systemic Position
Published on: April 1, 2022
Progressive pulmonary autograft root dilatation and failure after Ross procedure
J J Takkenberg1, P E Zondervan, L A van Herwerden
1Department of Cardio-pulmonary Surgery, Heart Center, Dijkzigt Hospital and Erasmus University, Rotterdam, The Netherlands. Takkenberg@thch.azr.nl
Abstract:
We present a case of progressive pulmonary autograft root dilatation and subsequent failure after a Ross procedure. The explanted autograft vessel wall revealed striking histologic findings indicative of chronic media rupture. Examination of another explanted pulmonary autograft root showed similar histologic changes, suggesting a common phenomenon in pulmonary autograft roots. It may be the cause of progressive root dilatation as observed after Ross operations.

