Translocation (2;3)(p21;q26) as the sole anomaly in a case of primary myelofibrosis
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Updated: Oct 23, 2026
07:34
FISH for Pre-implantation Genetic Diagnosis
Published on: February 23, 2011
C Herens1, J P Hermanne, F Tassin
1Department of Human Genetics, University of Liège, Belgium.
Cancer Genetics and Cytogenetics
|April 13, 1999
Abstract:
Translocation t(2p;3q) is a rare but recurrent finding in myeloid disorders. We present the first case of primary myelofibrosis with t(2;3)(p21;q26) as the sole chromosomal anomaly. The comparison with the 11 other previously published myeloid-associated t(2p;3q) cases confirms that this nonrandom translocation involves a pluripotent stem cell and is associated with a poor prognosis.
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