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Iron, thermoregulation, and metabolic rate.

P H Rosenzweig¹, S L Volpe

¹University of Massachusetts, Department of Nutrition, Chenoweth Lab, Amherst 01003-1420, USA.

Critical Reviews in Food Science and Nutrition

|April 13, 1999

Summary

Iron deficiency anemia impacts metabolic rate and body temperature regulation. Studies show iron deficiency elevates norepinephrine, increasing metabolic rate and potentially slowing growth.

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Area of Science:

Physiology
Nutritional Science
Biochemistry

Background:

Iron is crucial for oxygen transport and enzyme function in energy metabolism and thermoregulation.
Iron deficiency anemia (IDA) affects physiological functions, impacting both exercise and resting states.

Purpose of the Study:

To review the effects of iron deficiency on metabolic rate.
To examine the impact of iron deficiency on thermoregulation.

Main Methods:

Review of existing studies on iron depletion and iron deficiency anemia.
Analysis of physiological changes in both animal and human subjects.

Main Results:

Iron deficiency and IDA are linked to elevated norepinephrine levels in blood and urine.
Increased metabolic rate may result from iron deficiency, leading to reduced growth and body weight.

Conclusions:

Iron deficiency significantly affects metabolic rate and thermoregulation.
Norepinephrine elevation is a key physiological change associated with iron deficiency anemia.

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