[The effect of contrast agents on latex phagocytosis by mouse neutrophils]

The authors studied the effect of radiopaque agents (ROA):triombrast, omnipak, and ultravist and that of magnetoresonant contrast agents: omniscan and magnevist in concentration ranges (10(-4)-10(-2) M) on the phagocytizing activity of mouse neutrophils. All contrast agents inhibitors absorption of latex fragments by the neutrophils. A strong correlation was revealed between the osmotic activity of the radiopaque agents under study and the degree of suppression of neutrophil phagocytizing activity.