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Updated: Aug 10, 2026
07:06
Particle Agglutination Method for Poliovirus Identification
Published on: April 20, 2011
Poliovirus immunizations. What goes around, comes around
1Laboratory of Clinical Investigation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Infectious Disease Clinics of North America
|April 13, 1999
Summary
New polio vaccination guidelines aim to protect against wild poliovirus and prevent vaccine-associated paralytic poliomyelitis (VAPP) cases. These updated recommendations address ongoing concerns despite the eradication of wild poliovirus in the Western Hemisphere.
Area of Science:
- Public Health
- Vaccinology
- Infectious Disease Epidemiology
Background:
- Wild type poliovirus has been eradicated from the Western Hemisphere.
- Vaccine-associated paralytic poliomyelitis (VAPP) remains a concern.
- Existing polio vaccination protocols are being re-evaluated.
Purpose of the Study:
- To summarize recent changes in Advisory Committee on Immunization Practices (ACIP) recommendations for polio vaccination.
- To address the continued risk of VAPP.
- To outline strategies for the elimination of VAPP.
Main Methods:
- Review of current ACIP recommendations for poliovirus vaccination.
- Analysis of VAPP epidemiology.
- Assessment of vaccination strategies for disease prevention.
Main Results:
- The Western Hemisphere is free of wild poliovirus.
- VAPP continues to occur in individuals receiving the oral poliovirus vaccine or their contacts.
- Updated ACIP recommendations have been issued.
Conclusions:
- The updated polio vaccination recommendations aim to maintain protection against poliovirus.
- The goal is to eliminate VAPP cases in vaccine recipients and their contacts.
- Continued vigilance and adherence to new guidelines are crucial for polio eradication efforts.
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