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Tuberculous empyema.

K J Bai1, I H Wu, M C Yu

  • 1Department of Clinical Service, Taiwan Provincial Chronic Disease Control Bureau, Taipei.

Respirology (Carlton, Vic.)
|April 14, 1999
PubMed
Summary
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Tuberculous empyema treatment outcomes were less successful than pulmonary tuberculosis, with a 62.9% success rate. Multidrug chemotherapy and surgery offer hope for better results in managing this serious lung condition.

Area of Science:

  • Pulmonology
  • Infectious Diseases
  • Thoracic Surgery

Background:

  • Tuberculous empyema presents with nonspecific symptoms and advanced lung lesions.
  • Effusions often show neutrophilic leukocytosis and Mycobacterium tuberculosis presence.

Purpose of the Study:

  • To retrospectively investigate the clinical courses and treatment outcomes of tuberculous empyema patients.
  • To evaluate the efficacy of chemotherapy and surgical interventions.

Main Methods:

  • Retrospective analysis of 35 tuberculous empyema patients from November 1990 to November 1995.
  • Review of clinical data, chest roentgenographs, and laboratory findings.
  • Assessment of treatment regimens including chemotherapy and surgery.

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Main Results:

  • Most patients had nonspecific symptoms and advanced pulmonary lesions.
  • A 60% positive culture rate for Mycobacterium tuberculosis was observed, with multidrug-resistant strains in 7/18 cultures.
  • Successful treatment was achieved in 22 (62.9%) patients; 11.4% died of tuberculosis.

Conclusions:

  • Tuberculous empyema treatment outcomes are less satisfactory than pulmonary tuberculosis.
  • Modern multidrug chemotherapy, repeated drainage, and timely surgery show promise for successful treatment.