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Domain organization and oligomerization among H-NS-like nucleoid-associated proteins in bacteria
C J Dorman1, J C Hinton, A Free
1Dept of Microbiology, Moyne Institute of Preventive Medicine, University of Dublin, Trinity College, Ireland. cjdorman@tcd.ie
Trends in Microbiology
|April 21, 1999
Abstract:
The bacterial nucleoid-associated proteins H-NS and StpA can form homomeric or heteromeric complexes, a parallel with protein HU. Thus, functional modulation of H-NS and StpA by one another and by other proteins with appropriate interaction domains is possible. This has implications for bacterial pathogenesis and adaptation to environmental stress.