Related Experiment Video
Updated: Jul 24, 2026

Working with Human Tissues for Translational Cancer Research
Published on: November 26, 2015
Improving the request process to increase family consent for organ donation
S L Gortmaker1, C L Beasley, E Sheehy
1Dept of Health and Social Behavior, Harvard School of Public Health, Boston, MA 02115, USA. sgortmak@hsph.harvard.edu
Abstract:
The greatest impediment to organ donation is refusal of family consent. This study examined the impact of 3 modifiable elements of the donation request on family consent rates: (1) decoupling (i.e., the family understands and accepts brain death before discussion of organ donation is begun); (2) the procurement coordinator participates in the request for consent; and (3) donation is requested in a quiet, private place. Data on the request process were collected prospectively for 707 medically suitable potential donors who had been referred to 3 organ procurement organizations. The average rate of consent for donation was 62.2%. Higher consent rates were independently associated with the 3 characteristics studied. These components were summarized in the Request Process Scale. Multivariate regression analyses indicated that consent rates can be as high as 74% when all 3 process elements are present. Hospitals and organ procurement organizations should incorporate these elements into their standard of practice when requesting organ donation.
Related Concept Videos
Persuasion Strategies
Ethical Dilemmas II
Bone Marrow Sampling and Transplants
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
Tissue Transplantation
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
Kidney Transplant I: Introduction
Kidney Transplant II: Surgical Procedure

