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Chemomechanical removal of dental caries in deciduous teeth: further studies in vitro
H K Yip1, A G Stevenson, J A Beeley
1University of Hong Kong, Prince Philip Dental Hospital, Hong Kong.
Objective:
To further investigate the efficacy of N-monochloro-DL-2-aminobutyrate (NMAB) and NMAB containing 2 M urea (NMAB-urea) as chemomechanical caries removal reagents in deciduous teeth using standardised lesions and limited applicator pressure.
Design:
In vitro.
Method:
Carious dentine was removed from standardised lesions in deciduous teeth using NMAB, NMAB-urea or isotonic saline (control); 50 lesions were studied with each reagent. The surface of the dentine remaining in cavities where complete caries removal was achieved was examined by light and scanning electron microscopy.
Main Results:
NMAB-urea (but not NMAB) gave significantly improved caries removal compared with saline. The dentine surfaces remaining after complete caries removal were irregular and approximately one third were bacterially contaminated.
Conclusions:
The improved efficacy of NMAB by the addition of urea has been confirmed. Toxicity studies are still necessary prior to clinical use of this reagent.
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