Androgen receptors in two androgen-mediated, sexually dimorphic characters of frogs

The presence/absence of androgen receptors is examined in two sexually dimorphic features of frogs: the nuptial pad and the external oblique muscle. Immunohistochemistry reveals that both males and females possess androgen receptors in these tissues. Males have a higher density of immunopositive nuclei in the oblique muscle than do females. The presence of androgen receptors in both male and female tissues is consistent with results from hormone experiments in which androgen supplements induce the expression of a nuptial pad and enlarge the external oblique muscles in castrated males and ovariectomized females.