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CRBP I and CRABP I localisation during olfactory nerve development
A L Gustafson1, U Eriksson, L Dencker
1Department of Pharmaceutical Bioscience, Division of Toxicology, Uppsala Biomedical Centre, Uppsala University, Box 594, 751 24, Uppsala, Sweden. annelee.gustafson@tox.uu.se
Brain Research. Developmental Brain Research
|April 21, 1999
Abstract:
Retinoic acid appears to play a role during the formation of the olfactory system. Immunohistochemistry was used to localise the cellular retinoid binding-proteins for retinol (CRBP I) and retinoic acid (CRABP I) in the embryonic and adult olfactory system. Our results indicate that RA produced by the CRBP I-expressing 'glia-like' cells may act as a neurotrophic factor for the CRABP I-expressing immature olfactory axons.