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[Spinocerebellar ataxia and polyneuropathy secondary to vitamin E deficiency]
C Guiraud-Chaumeil1, F Battaglia, C Tranchant
1Service des Maladies du Système Nerveux et du Muscle, Hôpitaux Universitaires, Strasbourg.
Background:
Cerebellar ataxia or peripheral neuropathy can be signs of vitamin E deficiency. We report two cases.
Case Reports:
Two patients developed vitamin E deficiency subsequent to intestinal malabsorption. The first patient had a duodenogastric communication and dilatation of the first jejunal loop. The second patient had deficient pancreas secretion and dilatation of the biliary tree.
Discussion:
Vitamin E deficiency is generally secondary to acquired or hereditary malabsorption syndrome. It can also occur in the absence of malabsorption by hereditary deficiency in alpha-tocopherol transporter. Vitamin E supplements are required for malabsorption. The etiology work-up of neuropathy or cerebellar ataxia should include vitamin E assay.