[Mechanisms of intestinal bacterial toxemia in severe burns]

Electron-microscopy investigations of the small intestine mucosa in white rats with deep thermal burns of 18-20% of the body surface showed that already in early periods following the trauma grave thermal burns caused structural desorganization of the enterocytic barrier and invasion of the intestinal microflora. Damages of the wall of capillaries of the small intestine mucosa, being in themselves manifestations of generalized lesion of the histo-hematic barriers in burns, contributed to further invasion of microflora and its vital activity products into the blood. During the investigation a morphological picture of the phenomenon of endotoxinemia and bacteriemia developed already in the early periods of the burn trauma was established.