Endoscopic sinus surgery improves pulmonary function in patients with asthma associated with chronic sinusitis

Area of Science:

• Otolaryngology
• Pulmonology
• Allergy & Immunology

Background:

• Chronic sinusitis frequently coexists with asthma, complicating patient management.
• Sinus-related symptoms can exacerbate asthma control and pulmonary function.

Purpose of the Study:

• To evaluate the clinical efficacy of endonasal endoscopic sinus surgery (ESS) in patients with asthma and chronic sinusitis.
• To assess the impact of ESS on sinus symptoms, pulmonary function, and medication requirements.

Main Methods:

• A prospective study involving 21 patients with chronic sinusitis and asthma.
• 15 patients underwent bilateral endonasal ESS; 6 served as a control group.
• Pre- and postoperative assessments included symptom questionnaires, peak expiratory flow, and systemic glucocorticoid dosage.

Main Results:

• ESS group showed significant improvement in sinus-related symptoms 6 months postoperatively.
• Peak expiratory flow increased in the ESS group (40-190 L/min).
• Seven patients reduced corticosteroid needs; 4 required none post-surgery. Control group showed no significant changes.

Conclusions:

• Successful endonasal endoscopic sinus surgery can alleviate pulmonary dysfunction in asthma patients with chronic sinusitis.
• Treating chronic sinusitis effectively can reduce both sinus and asthma-related symptoms and signs.