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[Glucocorticoid deficiency of the adrenal cortex in chronic liver diseases]
Terapevticheskii Arkhiv
|May 1, 1999
Abstract
Aim:
The study of blood levels of hydrocortisone and ACTH in patients with chronic hepatic lesions.
Materials And Methods:
Blood levels of hydrocortisone and ACTH were measured in 198 patients with chronic liver diseases (CLD) of different etiology and severity and in 39 healthy controls.
Results:
Blood hydrocortisone was subnormal while ACTH elevated in all the patients except those with chronic hepatitis running a favorable course. Changes in the hydrocortisone and ACTH content were the greatest in CLD of viral and autoimmune etiology, the least--of alcoholic etiology.
Conclusion:
Hydrocortisone deficiency was most prominent in severe hepatic lesions.