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Structure and validation of a pharmacokinetic model for benzene
G C Sinclair1, C N Gray, R J Sherwood
1Occupational Hygiene Unit, Deakin University, Victoria, Australia. Georgia.Sinclair@bigpond.com
American Industrial Hygiene Association Journal
|May 1, 1999
Abstract:
A pharmacokinetic model for benzene has been developed and validated for the inhalation aspects of its operation. The validation shows reasonable agreement between the model outputs and human biological data for phenol in urine, benzene in alveolar air, and benzene in mixed exhaled air.