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Two dimensions and two States in DNA nanotechnology.

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Algorithmic Self-Assembly of DNA: Theoretical Motivations and 2D Assembly Experiments.

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Using lateral capillary forces to compute by self-assembly.

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On the reduction of errors in DNA computation.

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A sticker-based model for DNA computation.

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Computation of Atmospheric Concentrations of Molecular Clusters from ab initio Thermochemistry
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Published on: April 8, 2020

On applying molecular computation to the data encryption standard.

L M Adleman1, P W Rothemund, S Roweis

  • 1Department of Computer Science, University of Southern California, Los Angeles 90089, USA.

Journal of Computational Biology : a Journal of Computational Molecular Cell Biology
|May 1, 1999
PubMed
Summary
This summary is machine-generated.

Molecular computation offers a novel approach to breaking the Data Encryption Standard (DES). This DNA-based attack could be feasible on a small scale, even with significant errors.

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Area of Science:

  • Cryptography
  • Molecular Computation
  • Biotechnology

Background:

  • The United States Data Encryption Standard (DES) is a widely used symmetric-key algorithm.
  • Molecular computation presents a new paradigm for complex computational tasks.

Purpose of the Study:

  • To describe a molecular computation attack on the Data Encryption Standard (DES).
  • To analyze the feasibility of such an attack using the sticker model.

Main Methods:

  • Utilizing the sticker model of molecular computation.
  • Analyzing the requirements for a DES attack using DNA-based computation.

Main Results:

  • A molecular computation attack on DES is theoretically possible.
  • The attack could be implemented using approximately one gram of DNA.
  • The attack may succeed despite a high error rate.

Conclusions:

  • Molecular computation, specifically using DNA, presents a potential threat to DES security.
  • Tabletop-scale molecular computing devices could be capable of cryptographic attacks.