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Related Experiment Video

Updated: Jul 23, 2026

Bovine Mammary Gland Biopsy Techniques
14:53

Bovine Mammary Gland Biopsy Techniques

Published on: December 23, 2018

Experience with breast biopsies using the Advanced Breast Biopsy Instrumentation system.

A J Leibman1, D Frager, P Choi

  • 1Columbia University College of Physicians and Surgeons, St. Luke's-Roosevelt Hospital Center, New York, NY 10025, USA.

AJR. American Journal of Roentgenology
|May 5, 1999
PubMed
Summary

The advanced breast biopsy instrumentation (ABBI) procedure is less effective than core needle biopsy for diagnosing breast lesions. ABBI offered no advantages for benign or malignant findings and often failed to completely excise cancerous tumors.

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Area of Science:

  • Radiology
  • Surgical Pathology

Background:

  • Mammography is crucial for detecting breast lesions.
  • Advanced Breast Biopsy Instrumentation (ABBI) is a tool for excisional biopsy.
  • Limited data exists on ABBI's efficacy in radiology literature.

Purpose of the Study:

  • To evaluate the efficacy of ABBI for excisional breast biopsy.
  • To compare ABBI with other biopsy methods for mammographically detected lesions.

Main Methods:

  • Retrospective review of 53 patients with 54 mammographically detected lesions.
  • Biopsies performed using the ABBI system with cannulas from 5-20 mm.
  • Indications included calcifications (n=22) and masses (n=31).

Main Results:

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  • 45 benign results (fibroadenoma, cysts, etc.) with average specimen size 4.8 cm.
  • 7 malignancies diagnosed; 6 had involved margins, indicating incomplete excision.
  • One non-diagnostic biopsy for dermal calcifications; one atypia requiring reexcision for intraductal carcinoma.

    • Conclusions:

    • ABBI is more invasive and less available than core needle biopsy for benign lesions.
    • ABBI completely excised only one of seven malignant lesions.
    • ABBI offered no advantages over core needle biopsy for benign or malignant breast lesions.