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Risks of endoscopy in hospitalized pediatric patients with collagen vascular diseases
B C Weselman1, D B Friedman, R W Warren
1Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Houston, Texas, USA.
Insights
Endoscopy in pediatric patients with collagen vascular diseases can yield valuable insights for management. However, careful risk-benefit assessment is crucial due to potential serious complications.
Area of Science:
- Pediatric Gastroenterology
- Rheumatology
- Medical Procedures
Background:
- Gastrointestinal (GI) symptoms are common in pediatric collagen vascular diseases.
- Endoscopy is frequently indicated for these symptoms.
- Risks and benefits of endoscopy in this population are not well-established.
Purpose of the Study:
- To examine the risks and benefits of endoscopic procedures in pediatric patients with collagen vascular diseases.
- To analyze complications and outcomes associated with endoscopy in this cohort.
Main Methods:
- Retrospective review of pediatric patients with collagen vascular diseases hospitalized over a 7-year period.
- Identification of patients who underwent upper or lower endoscopy.
- Analysis of indications, complications, and outcomes.
Main Results:
- Nine patients (5%) underwent endoscopy; indications included abdominal pain, GI bleeding, vomiting, and diarrhea.
- Two patients experienced complications requiring surgery; one died from GI bleeding.
- Endoscopy led to management changes in five patients, including H. pylori treatment and optimized esophagitis/gastritis management.
- Vasculopathy was associated with complications.
Conclusions:
- Endoscopy can provide valuable information for managing pediatric patients with GI symptoms and collagen vascular diseases.
- Serious, potentially life-threatening complications can occur.
- Careful evaluation of the risk/benefit ratio is essential before performing endoscopy in these patients.
Background:
The gastrointestinal manifestations of the collagen vascular diseases have been well described in the pediatric population. These patients frequently have symptoms that constitute indications for endoscopy. However, the risks and benefits of endoscopy in this population have not been examined.
Methods:
A retrospective review of all patients with collagen vascular diseases hospitalized during a 7-year period was undertaken, and those patients who underwent endoscopy were identified.
Results:
Nine patients (5%) underwent endoscopic procedures (eight upper and three lower endoscopy). Complications and outcomes were analyzed. Indications for endoscopy included abdominal pain, gastrointestinal (GI) bleeding, and/or vomiting and diarrhea. Two patients had complications that required surgery within 1 day of the endoscopic procedure. One of these patients subsequently died with GI bleeding. Five of the nine patients had changes in their management after endoscopy. Helicobacter pylori infection was identified and treated in two patients. Three patients had esophagitis or gastritis and acid suppression treatment was started or optimized. Vasculopathy was present in the patients who had complications.
Conclusions:
This series suggests that endoscopy can provide useful information for the management of the pediatric patient with GI symptoms and collagen vascular diseases. However, because serious and potentially life-threatening complications can occur, great care is needed in evaluating the risk/benefit ratio of endoscopy in these patients.
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