Related Experiment Video
Updated: Oct 23, 2026
Doppler Ultrasonography for Live Imaging and Quantification of Ovarian Vascular Function in Mice
Published on: November 14, 2025
[Ultrasonic monitoring as a method of preventing risks of ovarian hyperstimulation during drug therapy]
R Grio1, A Patriarca, L Ramondini
1Dipartimento di Scienze Ginecologiche Ostetriche, Università degli Studi, Torino.
Background And Aims:
Ultrasonographic monitoring represents the most immediate method for an early confirmation of the onset of the worst complication of the pharmacological induction of ovulation: ovarian hyperstimulation. The aim of this study was to evaluate the incidence of this complication in a sample group of anovulatory patients receiving pharmacological treatment and undergoing repeated ultrasonographic monitoring.
Methods:
The authors analysed the controls performed during 1996-1997 in which a total of 413 cycles were stimulated. The patients included in the study group (mean age 28.5 years) were treated using clomiphene, oestradiol, FSH, LH and GnRH, and in 5 cases stimulation was preceded by suppression of the menstrual cycle using tryptorelin. Each patient was monitored with 3 scans, except for those treated with tryptorelin or GnRH who were more closely monitored.
Results:
In 413 patients included in this study the authors noted the onset of slight hyperstimulation in 6 cases (1.45%) which then resolved spontaneously without the need for hospitalisation.
Conclusions:
The authors affirm that ultrasonographic monitoring represents a valid means of controlling and preventing the risks of ovarian hyperstimulation.
