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Synthesis and biological studies of catechol ether type derivatives as potential phosphodiesterase (PDE) IV
1Department of Medicinal Chemistry, Cheil Jedang Corp., Kyonggi-Do, Korea. ckrhee@www.cheiljedang.com
Archives of Pharmacal Research
|May 7, 1999
Abstract:
New series of catechol ether type derivatives 5, 6 have been synthesized and applied to biological tests. Even though it is a preliminary data, some of our target molecules show the promising result against PDE IV inhibition. SAR and biological studies with synthetic compounds will be discussed in detail.