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Basic research conducted on alloplant biomaterials
E R Muldashev1, S A Muslimov, R T Nigmatullin
1Russian Eye and Plastic Surgery Center, Ufa, Russia.
Purpose:
To reduce antigenicity of allografts and stimulate their replacement by natural recipient tissues.
Methods:
Experimental allotransplantation of different tissues (fascias, tendons, derma, fat, etc.) with histological, histochemical, electron microscopical, electron histochemical examination 3, 5, 7, 14, 21, 30, 60, 120, 180 and 360 days postoperatively.
Results:
Allografts of different tissues with glucosaminoglycans extracted from collagen fibers have low antigenicity and can be replaced by natural tissues. Allografts with these properties were named 'Alloplant'.
Conclusions:
Alloplant biomaterials can selectively stimulate natural tissue regeneration. Hence, Alloplant biomaterials can be utilized in surgery for the restoration of different tissues.
