Synthesis and screening of some substituted 3.5-dioxopyrazolidines

Seven new 3.5-dioxopyrazolidine derivatives, incorporating in their molecule a p-substituted benzoyl grouping, were synthesized. The preliminary screening of four selected compounds showed that 1-phenyl-2-[p-nitrobenzoyl]-4.4-diethyl-3.5-dioxopyrazolidine possesses a low order of antiinflammatory activity.