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Related Experiment Videos

Limited ileal resection in infancy: the long-term consequences.

B W Davies1, G Abel, J W Puntis

  • 1Department of Paediatric Surgery, Leeds Teaching Hospitals Trust and Centre for Bone and Body Composition Research, University of Leeds, England.

Journal of Pediatric Surgery
|May 11, 1999
PubMed
Summary

Children with limited ileal resection in infancy show good growth and nutrition. However, necrotizing enterocolitis (NEC) increases the risk of gallstones and vitamin B12 deficiency.

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Area of Science:

  • Pediatric Surgery
  • Gastroenterology
  • Nutritional Science

Background:

  • Limited information exists on the long-term nutritional and metabolic effects of small (less than 50 cm) ileal resections in infants.
  • Understanding these sequelae is crucial for developing appropriate follow-up strategies for affected children.

Purpose of the Study:

  • To investigate the long-term nutritional, metabolic, and clinical outcomes in children who underwent limited ileal resection in infancy.
  • To assess the prevalence of specific complications such as vitamin deficiencies, renal calculi, and cholelithiasis following ileal resection.

Main Methods:

  • A cohort of children who had limited ileal resection for necrotizing enterocolitis (NEC) or intussusception between 1984 and 1992 were evaluated.
  • Assessments included clinical examination, anthropometry, hematologic and biochemical tests, ultrasound, and bone mineral density measurements.

Related Experiment Videos

  • A control group of children with neonatal NEC who did not undergo surgery was also included for comparison.

    • Main Results:

    • Twenty-four children (17 NEC, 7 intussusception) with a median age of 7.4 years participated.
    • Growth parameters (height, weight, BMI) were generally within normal percentiles (25th-50th).
    • One child had asymptomatic vitamin B12 deficiency, three had low vitamin A, and four (24%) developed cholelithiasis, all with prior NEC. Trace element levels were occasionally low in both groups.

    Conclusions:

    • Limited ileal resection in infancy is associated with preserved growth and nutritional status.
    • Necrotizing enterocolitis (NEC) as a reason for limited ileal resection is linked to a high prevalence of cholelithiasis (gallstones).
    • A risk of vitamin B12 deficiency exists after limited ileal resection, necessitating careful long-term follow-up planning.