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Therapeutic substitution: has its time arrived?
Summary
Therapeutic substitution, where a hospital pharmacy dispenses a different but equivalent drug, is not widely understood. A 1980 survey revealed its adoption and discussed its pros and cons.
Area of Science:
- Pharmacy Practice
- Health Services Research
Background:
- Therapeutic substitution involves dispensing a chemically different yet therapeutically equivalent drug.
- Hospital P&T Committee guidelines govern this practice.
- The national adoption rate of therapeutic substitution was previously unknown.
Purpose of the Study:
- To assess the extent of therapeutic substitution adoption in U.S. hospitals.
- To review the issues, findings, pros, and cons of therapeutic interchange.
- To provide an update on evolving therapeutic substitution procedures.
Main Methods:
- Conducted a nationwide survey of hospital pharmacies in late 1980.
- Collected data on the adoption and practices of therapeutic substitution.
Main Results:
- Findings regarding the extent of therapeutic substitution adoption were identified.
- Key issues, advantages, and disadvantages of therapeutic interchange were analyzed.
Conclusions:
- The study provided insights into the national landscape of therapeutic substitution.
- Recent changes in therapeutic substitution procedures were highlighted.