[Hydrophobic nucleus in the primary structure of bovine prolactin]

In the primary structure of bovine prolactin a hydrophobic fragment 79-88 of the peptide chain was found, which participated in a maintenance of conformation of the hormone molecule in a solution due to hydrophobic interactions. The fragment contained about 50% of leucine residues, which are currently considered as important in determination of three-dimensional structure and biological functions of protein (6).