Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Mood Disorders Secondary to Stroke.

Robinson1

  • 1Department of Psychiatry, University of Iowa College of Medicine, Iowa City, IA, USA

Seminars in Clinical Neuropsychiatry
|May 13, 1999
PubMed
Summary

Mood disorders after stroke are often secondary to cerebral infarction. Lesion location correlates with specific mood disorders, suggesting an etiological link requiring further investigation for targeted treatments.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Case of Abscess of the Liver, with a Formation of Hydatids.

The Medical and physical journal·2018
Same author

Stereotactic conformal radiotherapy for pituitary adenomas: technique and preliminary experience.

Clinical endocrinology·2017
Same author

NNTs and NNHs: an individualized way to present benefit and risk.

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland·2013
Same author

Selection of a Suitable Method for Analysis of Aflatoxins in Date Fruits.

Journal of agricultural and food chemistry·2001
Same author

Fate of

Journal of agricultural and food chemistry·2001
Same author

Low (Sub-1-volt) halfwave voltage polymeric electro-optic modulators achieved by controlling chromophore shape

Science (New York, N.Y.)·2001

Area of Science:

  • Neurology
  • Neuropsychiatry
  • Stroke Medicine

Background:

  • Mood disorders are a common complication following stroke, recognized for over a century.
  • Recent research investigates whether these mood disturbances are primary psychiatric conditions or secondary to brain injury.
  • Clinical observations show similarities between post-stroke mood disorders and primary mood disorders.

Purpose of the Study:

  • To determine if mood disorders following stroke are secondary to cerebral infarction.
  • To explore the etiological link between cerebral ischemia and mood disturbances.
  • To identify specific lesion locations associated with acute post-stroke mood disorders.

Main Methods:

  • Clinical-pathologic correlation during the acute post-stroke period.
  • Analysis of mood disorder symptoms in relation to lesion location.
  • Comparison of clinical phenomenology, longitudinal course, and treatment response with primary mood disorders.

Main Results:

  • Major depression post-stroke was significantly associated with left frontal and left basal ganglia lesions.
  • Manic episodes were linked to lesions in the right orbital frontal, basotemporal, basal ganglia, or thalamic regions.
  • Findings support an etiological connection between cerebral ischemia and mood disorders.

Conclusions:

  • Mood disorders in the acute post-stroke period are frequently etiologically linked to cerebral ischemia.
  • Identifying the underlying mechanisms will confirm the secondary nature of these disorders.
  • Understanding these mechanisms can lead to the development of more focused treatment strategies for post-stroke mood disturbances.

Related Experiment Videos