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The dynamics of HTLV-I and the CTL response
D Wodarz1, M A Nowak, C R Bangham
1Institute for Advanced Study, Olden Lane, Princeton, NJ 08540, USA.
Immunology Today
|May 14, 1999
Abstract:
Dominik Wodarz and colleagues describe a mathematical model for the in vivo dynamics of human T-cell leukaemia virus type 1 (HTLV-I) infection and the virus-specific cytotoxic T lymphocyte response. They show that a high rate of viral replication is consistent with the relative sequence invariance of HTLV-I and might be necessary to maintain a persistent infection.