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Updated: Aug 19, 2026

Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer
Published on: November 3, 2013
Reversibility of prostatic intraepithelial neoplasia: implications for chemoprevention
D G Bostwick1, R Neumann, J Qian
1Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minn. 55905, USA. bostwick.david@mayo.edu
Abstract:
High-grade prostatic intraepithelial neoplasia is the most likely precursor of prostatic adenocarcinoma, according to virtually all available evidence. It has a high predictive value as a marker for adenocarcinoma, and its identification in biopsy specimens of the prostate warrants further search for concurrent invasive carcinoma. Androgen deprivation therapy and radiation therapy decrease its prevalence and extent, suggesting a role in chemoprevention.

