[Changes in serum beta-N-acetylglucosaminidase activity in obesity patients treated with various diets and physical...

Changes in the serum activity of the lysosome enzyme beta-N-acetyl glucos aminidase are studied in 85 patients with varying degree alimentary overweight, undergoing treatment under sanatorial conditions with regimes including physical loading and a variety of diets: "free of carbohydrates" according to Atkins (31 cases), poor in fats (16 cases) and rich in fats (38 cases). The enzyme activity shows a statistically significant rise in the middle and at the end of treatment. The differences discovered are interpreted as an expression of the participation of lysosomes and their hydrolytic enzymes in the transition period to partial endogenous feeding which is connected with the increased permeability of lysosome and cellular membranes.