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Synthesis and properties of (6,7-dimethoxy-4-coumaryl)alanine: a fluorescent peptide label
F A Bennett1, D J Barlow, A N Dodoo
1Department of Pharmacy, King's College London, Manresa Road, London, SW3 6LX, United Kingdom.
Analytical Biochemistry
|May 18, 1999
Abstract:
The synthesis of racemic and l-(6,7-dimethoxy-4-coumaryl)alanine (Dmca) is described and some spectral and physicochemical properties are reported. The utility of Dmca as a highly sensitive and specific label for the quantitative detection of synthetic peptides in HPLC and in minimal essential media (MEM) is also described.