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Endocytosis: an assembly protein for clathrin cages
1MRC Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 2QH, UK.
Current Biology : CB
|May 20, 1999
Abstract:
The protein AP180 is known to have clathrin-assembly activity in vitro. AP180 has now been found to be crucial for synaptic vesicle endocytosis and the maintenance of a uniform-size vesicle population in vivo. These results significantly advance our understanding of clathrin-mediated endocytosis in the synapse and elsewhere.