Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Three-dimensional reconstruction in dermatopathology--a personal computer-based system.

T Matsumura1, K C Sato-Matsumura, T Yokota

  • 1Department of Dermatology, Hokkaido University School of Medicine, Sapporo, Japan. tetsuri@med.hokudai.ac.jp

Journal of Cutaneous Pathology
|May 21, 1999
PubMed
Summary

This study presents a 3D reconstruction system for dermatopathology using personal computers. The method creates high-quality 3D images of skin specimens, aiding in understanding structures and diagnosing tumors.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Isolation and characterization of avian influenza viruses from raw poultry products illegally imported to Japan by international flight passengers.

Transboundary and emerging diseases·2017
Same author

Differential effects of SH-reactive agents on [(3)H](+/-)-3-(2-carboxypiperazin-4-yl)propyl-1-phosphonate and [(3)H]glutamate binding in brain synaptic membranes treated with triton X-100.

Neurochemistry international·2010
Same author

Epidermotropic metastatic malignant melanoma with a pedunculated appearance.

Clinical and experimental dermatology·2003
Same author

Enhanced contact hypersensitivity in human monocyte chemoattractant protein-1 transgenic mouse.

Immunobiology·2002
Same author

High macrophage migration inhibitory factor (MIF) serum levels associated with extended psoriasis.

The Journal of investigative dermatology·2001
Same author

A new case of alpha-N-acetylgalactosaminidase deficiency with angiokeratoma corporis diffusum, with Ménière's syndrome and without mental retardation.

The British journal of dermatology·2001

Area of Science:

  • Dermatopathology
  • Medical Imaging
  • Computational Biology

Background:

  • Dermatopathological specimens are typically analyzed in 2D.
  • Understanding the 3D structure is crucial for accurate diagnosis.
  • Existing 3D reconstruction methods can be complex or costly.

Purpose of the Study:

  • To develop an accessible system for 3D reconstruction of dermatopathological specimens.
  • To utilize readily available personal computers and graphic software.
  • To generate high-fidelity 3D visualizations for diagnostic purposes.

Main Methods:

  • Serial sections of dermatopathological specimens were digitized.
  • A stereogram was generated using projection techniques.
  • Images were processed on a personal computer with graphic programs.

Related Experiment Videos

Main Results:

  • High-quality 3D images were achieved, revealing detailed structures like rete ridges and dermal papillae.
  • The method accurately visualized normal epidermis, seborrheic keratosis, and basal cell carcinoma.
  • The system effectively demonstrated 3D tumor nest proliferation and invasion patterns.

Conclusions:

  • The developed system provides an effective and accessible method for 3D reconstruction in dermatopathology.
  • This technique enhances the understanding of complex tissue architectures and tumor morphology.
  • It offers potential for improved differential diagnosis of malignant skin tumors.