Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

Open Angle Glaucoma: Treatment

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

Photoreceptors and Visual Pathways

Photoreceptors and Visual Pathways

At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category, whereas...

Complications of Diabetes Mellitus

Complications of Diabetes Mellitus

Diabetes mellitus is a chronic metabolic disorder characterized by persistent hyperglycemia due to insulin deficiency, resistance, or both. Prolonged hyperglycemia disrupts metabolic homeostasis and leads to acute and chronic complications.Acute ComplicationsAcute complications result from sudden metabolic imbalance.Diabetic ketoacidosis (DKA) mainly appears in type 1 diabetes but may also develop in type 2 diabetes, particularly under extreme stress. It arises from severe insulin deficiency,...

Diabetic Retinopathy

Diabetic Retinopathy

DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...

Diabetic Nephropathy

Diabetic Nephropathy

Definition Diabetic nephropathy is a chronic kidney complication that results from prolonged hyperglycemia.Prevalence It is the most common cause of chronic kidney disease (CKD) and end-stage renal disease (ESRD) worldwide, affecting up to half of individuals with diabetes.Pathophysiology • Sustained hyperglycemia triggers multiple hemodynamic and metabolic changes in the kidney. • Early in the disease, increased renal blood flow and glomerular hyperfiltration occur due to afferent arteriolar...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Comparative Efficacy of the SLT versus LASAG Nd: YAG Delivery Systems in Rabbits.

Journal of glaucoma·2009

Same author

Orbital solitary fibrous tumor: radiographic and histopathologic correlations.

Ophthalmic plastic and reconstructive surgery·2001

Same author

Ultrasonographic evidence of a mushroom-shaped choroidal metastasis.

American journal of ophthalmology·2000

Same author

Choroidal neovascularization with granulomatous inflammation in ocular histoplasmosis syndrome.

American journal of ophthalmology·2000

Same author

Localized neurofibroma of the orbit: a radiographic and histopathologic study.

Ophthalmic plastic and reconstructive surgery·2000

Same author

Cutaneous malignant melanoma metastatic to the eyelid.

Ophthalmic surgery and lasers·1998

Search research articles

Related Experiment Video

Updated: Jun 26, 2026

Behavioral Assessment of Visual Function via Optomotor Response and Cognitive Function via Y-Maze in Diabetic Rats

Behavioral Assessment of Visual Function via Optomotor Response and Cognitive Function via Y-Maze in Diabetic Rats

Published on: October 23, 2020

Ocular disease in the diabetic elderly.

¹Departments of Ophthalmology and Pathology, Saint Louis University Eye Institute, Saint Louis University School of Medicine, St. Louis, Missouri 63104, USA.

Clinics in Geriatric Medicine

|May 26, 1999

Summary

Diabetic retinopathy, an eye complication in older adults, can often be managed to prevent vision loss. However, many patients aren't receiving timely screenings and referrals, impacting their care.

Area of Science:

Ophthalmology
Endocrinology
Geriatrics

Background:

Diabetic retinopathy is a major cause of vision loss in elderly diabetic patients.
Early detection and intervention are crucial for preventing or delaying visual impairment.
Many patients do not adhere to established screening and referral guidelines.

Purpose of the Study:

To highlight the importance of timely referral for diabetic retinopathy management in older adults.
To emphasize the need for adherence to American College of Physicians/American Academy of Ophthalmology guidelines.
To underscore the potential for visual rehabilitation even when medical or surgical options are limited.

Main Methods:

Review of current guidelines for diabetic retinopathy screening and referral.

More Related Videos

Alternate Immersion in Glucose to Produce Prolonged Hyperglycemia in Zebrafish

Alternate Immersion in Glucose to Produce Prolonged Hyperglycemia in Zebrafish

Published on: May 5, 2021

An Assay to Detect Protection of the Retinal Vasculature from Diabetes-Related Death in Mice

An Assay to Detect Protection of the Retinal Vasculature from Diabetes-Related Death in Mice

Published on: January 12, 2024

Related Experiment Videos

Last Updated: Jun 26, 2026

Behavioral Assessment of Visual Function via Optomotor Response and Cognitive Function via Y-Maze in Diabetic Rats

Behavioral Assessment of Visual Function via Optomotor Response and Cognitive Function via Y-Maze in Diabetic Rats

Published on: October 23, 2020

Alternate Immersion in Glucose to Produce Prolonged Hyperglycemia in Zebrafish

Alternate Immersion in Glucose to Produce Prolonged Hyperglycemia in Zebrafish

Published on: May 5, 2021

An Assay to Detect Protection of the Retinal Vasculature from Diabetes-Related Death in Mice

An Assay to Detect Protection of the Retinal Vasculature from Diabetes-Related Death in Mice

Published on: January 12, 2024

Analysis of the impact of delayed or missed referrals on patient outcomes.

Discussion of visual rehabilitation strategies for patients with advanced disease.

Main Results:

Timely referral is critical for preventing, ameliorating, or delaying vision loss in diabetic retinopathy.
A significant number of older diabetic patients are not screened or referred according to established guidelines.
Adherence to guidelines is essential for providing optimal care and preventing vision loss.

Conclusions:

Improved adherence to screening and referral protocols is necessary to enhance care for older diabetic patients with retinopathy.
Early detection and management can significantly improve visual outcomes.
Visual rehabilitation services are vital for patients with impaired vision due to diabetic retinopathy.