Mechanisms of transcriptional regulation

The sequential activation and repression of the human PDGF-B gene during chronic hypoxia reveals antagonistic roles for the depletion of oxygen and glucose.

Growth factors (Chur, Switzerland)·2002

Inhibition of histone deacetylase activity causes cell type-specific induction of the PDGF-B promoter only in the absence of activation by its enhancer.

Experimental cell research·2001

A novel type of regulatory element is required for promoter-specific activity of the PDGF-B intronic enhancer region.

Growth factors (Chur, Switzerland)·1999

Cell-type-specific modulation of PDGF-B regulatory elements via viral enhancer competition: a caveat for the use of reference plasmids in transient transfection assays.

Gene·1996

Genomic imprinting and mammalian development.

Placenta·1996

An Inr-containing sequence flanking the TATA box of the human c-sis (PDGF-B) proto-oncogene promoter functions in cis as a co-activator for its intronic enhancer.

Oncogene·1995

Application of Bioactive Natural Compounds to Promote Cell Proliferation and Migration in the Wound Healing Process.

Results and problems in cell differentiation·2026

Mechanobiology of Myelin Generation/Regeneration in Health and Disease.

Results and problems in cell differentiation·2026

Epigenetic Regulation of RUNX2 in Bone Mechanobiology.

Results and problems in cell differentiation·2026

Integrating Mechanical Loading, Mechanotransduction, and Biological Responses in Musculoskeletal Tissues Across the Lifespan: Regulation Influenced by Cells, Extracellular Matrix, and Sex.

Results and problems in cell differentiation·2026

Ciliary-Mediated Mechanotransduction in Skeletal Development and Diseases.

Results and problems in cell differentiation·2026

Modulation of the Mechanosensory Matrisome by Serotonergic Signaling.

Results and problems in cell differentiation·2026

Nucleolar dynamics are determined by the ordered assembly of the ribosome.

The Journal of cell biology·2026

A Novel De Novo STAG1 Variant at the RAD21 Binding Interface Is Associated With Hypoglycemia, Recurrent Fever, Immunodeficiency and Features of Classical Cohesinopathies.

Clinical genetics·2026

The lifelong transcriptomic landscape of human blood cells.

Protein & cell·2026

Conservation of Long G4-rich (LG4) genomic enhancer regulations.

BMC genomics·2026

Genome-wide characterization of the bZIP gene family in Rattus norvegicus and expression profiling analysis during brain development.

BMC genomics·2026

In vitro reconstitution of chromatin replication recapitulates symmetric histone recycling.

Nature communications·2026

Related Experiment Videos

Mechanisms of transcriptional regulation

Related Concept Videos

The sequential activation and repression of the human PDGF-B gene during chronic hypoxia reveals antagonistic roles for the depletion of oxygen and glucose.

Inhibition of histone deacetylase activity causes cell type-specific induction of the PDGF-B promoter only in the absence of activation by its enhancer.

A novel type of regulatory element is required for promoter-specific activity of the PDGF-B intronic enhancer region.

Cell-type-specific modulation of PDGF-B regulatory elements via viral enhancer competition: a caveat for the use of reference plasmids in transient transfection assays.

Genomic imprinting and mammalian development.

An Inr-containing sequence flanking the TATA box of the human c-sis (PDGF-B) proto-oncogene promoter functions in cis as a co-activator for its intronic enhancer.

Application of Bioactive Natural Compounds to Promote Cell Proliferation and Migration in the Wound Healing Process.

Mechanobiology of Myelin Generation/Regeneration in Health and Disease.

Epigenetic Regulation of RUNX2 in Bone Mechanobiology.

Integrating Mechanical Loading, Mechanotransduction, and Biological Responses in Musculoskeletal Tissues Across the Lifespan: Regulation Influenced by Cells, Extracellular Matrix, and Sex.

Ciliary-Mediated Mechanotransduction in Skeletal Development and Diseases.

Modulation of the Mechanosensory Matrisome by Serotonergic Signaling.

Nucleolar dynamics are determined by the ordered assembly of the ribosome.

A Novel De Novo STAG1 Variant at the RAD21 Binding Interface Is Associated With Hypoglycemia, Recurrent Fever, Immunodeficiency and Features of Classical Cohesinopathies.

The lifelong transcriptomic landscape of human blood cells.

Conservation of Long G4-rich (LG4) genomic enhancer regulations.

Genome-wide characterization of the bZIP gene family in Rattus norvegicus and expression profiling analysis during brain development.

In vitro reconstitution of chromatin replication recapitulates symmetric histone recycling.

Related Experiment Videos

Mechanisms of transcriptional regulation

Related Concept Videos

Related Articles