Related Experiment Videos
[Rhabdomyolysis associated with disseminated gonococcal infection in an elderly woman]
S Attorri1, S Salomón, J Carena
1Hospital Luis Lagomaggiore, Facultad de Ciencias Médicas, Universidad Nacional de Cuyo, Mendoza, Argentina.
Abstract:
Disseminated Gonococcal Infection (DGI) is very unusual in elderly patients and its association with Rhabdomyolysis (RML) has not been published for which reason we are presenting a case of RML secondary to DGI in an elderly women. We presume that the muscle damage was directly related with the gonococcal infection through toxin generation and release of endogenous mediators from mononuclear phagocytes and neutrophils and/or with ischemic injury due to altered tissue perfusion evidenced in this case by the presence of hypotension, oliguria and acidosis. We suggest that DGI be added to the RML infectious etiologies and considered in the initial differential diagnosis of all patients with polyarthritis and RML in order to facilitate an optimal treatment.
Insights
Disseminated Gonococcal Infection (DGI) is rarely seen in elderly patients. This case report highlights Rhabdomyolysis (RML) as a potential complication of DGI in this population.
Area of Science:
- Infectious Diseases
- Nephrology
- Rheumatology
Background:
- Disseminated Gonococcal Infection (DGI) is uncommon in the elderly.
- The association between DGI and Rhabdomyolysis (RML) has not been previously documented.
Observation:
- A case of Rhabdomyolysis (RML) secondary to Disseminated Gonococcal Infection (DGI) in an elderly woman is presented.
- The patient exhibited hypotension, oliguria, and acidosis, suggesting ischemic injury and altered tissue perfusion.
Findings:
- Muscle damage in RML secondary to DGI is presumed to result from direct gonococcal effects, toxin release, inflammatory mediators, or ischemic injury.
- This case suggests a potential link between gonococcal infection and Rhabdomyolysis.
Implications:
- DGI should be considered an infectious etiology for Rhabdomyolysis (RML).
- Clinicians should include DGI in the differential diagnosis for elderly patients presenting with polyarthritis and RML.
- Early consideration of DGI can facilitate optimal treatment and patient outcomes.