[Analysis of total lactate dehydrogenase isoenzyme activity in mouse ova during clevage]

The total activity of lactate dehydrogenase isoenzymes was detected in the intact ova of mice during the clevage and, in particular, blastomeres at the 2-cell stage. Routine histochemical technique was employed in addition to microspectrometry. During the clevage, the ova differ in their enzyme activity. At the 2-cell stage there are ova with similar reaction in both the blastomeres as well as those with different enzyme activity in each blastomere.