Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Protein import into chloroplasts.

X Chen1, D J Schnell

  • 1Dept of Biological Sciences, Rutgers, The State University of New Jersey, 101 Warren Street, Newark, NJ 07102, USA.

Trends in Cell Biology
|June 4, 1999
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Functions and origins of the chloroplast protein-import machinery.

Essays in biochemistry·2002
Same author

Dose-response relations of azimilide in the management of symptomatic, recurrent, atrial fibrillation.

The American journal of cardiology·2001
Same author

Peroxisomal protein import. the paradigm shifts.

Cell·2001
Same author

Antiarrhythmic effects of azimilide in atrial fibrillation: efficacy and dose-response. Azimilide Supraventricular Arrhythmia Program 3 (SVA-3) Investigators.

Journal of the American College of Cardiology·2000
Same author

Mechanism of protein import across the chloroplast envelope.

Biochemical Society transactions·2000
Same author

The transit sequence of ferredoxin contains different domains for translocation across the outer and inner membrane of the chloroplast envelope.

The Journal of biological chemistry·2000
Same journal

Horizontal transfer of mitochondria in cancer: The physiology reborn in disease?

Trends in cell biology·2026
Same journal

Spindle errors: A stress test for epithelial robustness.

Trends in cell biology·2026
Same journal

Multicellular ecosystems: Linking cellular diversity to tissue function and disease.

Trends in cell biology·2026
Same journal

Orchestrating the signaling-bias at the protease-activated receptor, PAR1.

Trends in cell biology·2026
Same journal

Crashing by design: Utilizing DNA damage for MCC differentiation.

Trends in cell biology·2026
Same journal

The value of a shared lab: Our insights.

Trends in cell biology·2026
See all related articles

Chloroplasts utilize two distinct membrane translocation systems to import proteins essential for photosynthesis and metabolism. These systems physically connect to move proteins from the cytoplasm into the chloroplast stroma.

Area of Science:

  • Plant Biology
  • Cell Biology
  • Biochemistry

Background:

  • Chloroplasts regulate photosynthesis, amino acid, and lipid metabolism through complex subcompartments.
  • Organellar biogenesis and maintenance depend on proteins encoded by nuclear and plastid genomes.
  • Nuclear-encoded proteins are imported into chloroplasts via their N-terminal transit sequences interacting with import machinery.

Purpose of the Study:

  • To review current understanding of chloroplast protein import translocation systems.
  • To discuss models for the function of these translocation systems.

Main Methods:

  • Literature review of recent investigations on chloroplast protein import.
  • Analysis of models describing the function of translocation systems.

Related Experiment Videos

Main Results:

  • Two unique membrane-bound translocation systems exist in the outer and inner chloroplast envelope membranes.
  • These systems physically associate during protein import.
  • They facilitate the transport of preproteins from the cytoplasm to the stromal compartment.

Conclusions:

  • The coordinated action of outer and inner envelope membrane translocation systems is crucial for chloroplast protein import.
  • Further research is needed to fully elucidate the functional mechanisms of these systems.