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Occupational protein contact dermatitis to cornstarch in a paper adhesive
J D Guin1, C Westfall, D Ruddell
1Department of Dermatology and the Department of Ophthalmology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Summary
Occupational contact dermatitis from cornstarch adhesive can occur in industrial settings. Testing for type 1 allergy is crucial for diagnosis when patch tests are negative.
Area of Science:
- Dermatology
- Occupational Medicine
- Allergology
Background:
- Protein contact dermatitis is commonly seen in healthcare and food service workers.
- Cornstarch is rarely a cause of contact dermatitis, but can induce contact urticaria from glove powder.
Observation:
- A paper-bag maker developed severe occupational contact dermatitis hours after returning to work.
- The patient showed no signs of urticaria and had negative patch test results.
Findings:
- Patch testing was negative, with only a mild reaction to the cornstarch adhesive.
- Prick testing to cornstarch resulted in a significant eczematous reaction lasting over ten weeks.
- Complete resolution of dermatitis occurred after avoiding cornstarch and the adhesive.
Implications:
- Occupational contact dermatitis without urticaria may necessitate type 1 allergy testing.
- This case highlights cornstarch as a potential allergen in occupational settings.
- Diagnostic protocols for occupational dermatitis should consider type 1 hypersensitivity.

