Software for real-time control of a tidal liquid ventilator

Area of Science:

• Biomedical Engineering
• Medical Device Software
• Respiratory Technology

Background:

• Liquid ventilation offers potential benefits for respiratory support.
• Precise control of ventilation parameters is crucial for patient outcomes.
• Existing systems may lack user-friendliness or advanced control capabilities.

Purpose of the Study:

• To develop and test computer software and control algorithms for a tidal liquid ventilator.
• To create a system enabling precise control over key ventilation parameters.
• To enhance user interaction and provide simulation capabilities for training.

Main Methods:

• Software developed using Microsoft Visual C++ with a graphic user interface and real-time, multithreaded operation.
• Control algorithms implemented via pump speed adjustment and solenoid valve positioning.
• Data acquisition through analog-to-digital conversion for monitoring and control.
• Operator-defined ventilation parameters, flow pulse shapes, and safety limits.

Main Results:

• The software successfully operated a prototype tidal liquid ventilator.
• Precise control of ventilation frequency, tidal volume, and inspiratory-expiratory ratio was achieved.
• The system allowed optimization of perfluorochemical liquid transfer while minimizing airway pressures.
• Data logging to Excel spreadsheets facilitated review and analysis of ventilation parameters.

Conclusions:

• The developed software and control algorithms provide user-friendly operation of a tidal liquid ventilator.
• The system offers precise control over ventilation parameters, enhancing safety and efficacy.
• The integrated simulator aids in user education for liquid ventilation principles.