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Effect of a new immunosuppressant, FTY720, on joint allografts
H Watanabe1, Y Hamada, T Toshima
1Department of Orthopaedic Surgery, Yamanashi Medical College, Nakakomagun, Yamanashi-Ken, Japan.
Journal of Reconstructive Microsurgery
|June 11, 1999
Abstract:
The immunosuppressive effects of a new agent, FTY720, on joint allografts were studied histologically in a rat model. Favorable results without side effects were obtained at a dose of 3.0 mg/kg/day. The authors believe that this agent is one of the most useful immunosuppressants in the reported experimental model.