Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Novel secretory pathways in Plasmodium?

D Mattei1, G E Ward, G Langsley

  • 1Unité de Biologie des Interactions Hôte-Parasite, URA 1960, Institut Pasteur, Paris 75015, France.

Parasitology Today (Personal Ed.)
|June 15, 1999
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

First Report of the Root Knot Nematode, Meloidogyne inornata, on Common Bean in Paraná State, Brazil.

Plant disease·2019
Same author

Impact of egg handling and conditions during extended storage on egg quality.

Poultry science·2017
Same author

Diurnal preference, mood and the response to morning light in relation to polymorphisms in the human clock gene PER3.

Scientific reports·2017
Same author

Maternal immune activation results in complex microglial transcriptome signature in the adult offspring that is reversed by minocycline treatment.

Translational psychiatry·2017
Same author

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme·2016
Same author

PKA and Apicomplexan Parasite Diseases.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme·2016
Same journal

Immune effector mechanisms in parasitic infections.

Parasitology today (Personal ed.)·2006
Same journal

Nitric oxide in health and disease.

Parasitology today (Personal ed.)·2006
Same journal

Infection, oxford general practice series 40.

Parasitology today (Personal ed.)·2006
Same journal

Parasitism and the platyhelminthes.

Parasitology today (Personal ed.)·2006
Same journal

Reply.

Parasitology today (Personal ed.)·2006
Same journal

Waterborne cryptosporidiosis and the need for legislation.

Parasitology today (Personal ed.)·2006
See all related articles

Investigating Plasmodium falciparum protein secretion reveals the proposed dual secretory system is not supported by current data. The study questions the uniqueness of Plasmodium

Area of Science:

  • Cell Biology
  • Parasitology
  • Molecular Biology

Background:

  • Protein secretion in intraerythrocytic Plasmodium falciparum remains poorly understood.
  • A recent model proposed two distinct, mutually exclusive secretory compartments within the parasite.
  • This model has garnered significant attention in the field.

Purpose of the Study:

  • To critically evaluate the data supporting the dual secretory compartment model for Plasmodium.
  • To explore the generalizability of unusual protein secretion mechanisms in Plasmodium to other eukaryotic cells.

Main Methods:

  • Critical analysis of existing experimental data.
  • Comparative review of protein secretion pathways across eukaryotic organisms.

Main Results:

Related Experiment Videos

  • The data currently available does not strongly support the existence of two distinct, mutually exclusive secretory compartments.
  • Aspects of Plasmodium protein secretion may share commonalities with general eukaryotic pathways.

Conclusions:

  • The proposed dual secretory system model for Plasmodium falciparum requires further robust evidence.
  • Plasmodium's protein secretion mechanisms may not be as unique as previously suggested, offering broader insights into eukaryotic cell biology.