[Clinical features of Cryptococcus neoformans infections]

Two cases of infection with Cryptococcus neoformans are presented. The first showed primary localization in the CNS, while the second occurred in connection with lymphoproliferative malignancy and cytotoxic chemotherapy, with the typical sequence of initial lung infection and secondary meningo-encepha-litis. The important clinical features, development and therapy of the disease are discussed in the light of this personal experience.