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Co-receptors on B lymphocytes

T Tsubata1

  • 1Department of Immunology, Medical Research Institute, Tokyo Medical andDental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8510, Japan. tsubata.imm@mri.tmd.ac.jp

Co-receptors have been shown to regulate the antigen-receptor signaling threshold for B cell responses by modulating the activation of signaling molecules that are essential for transmitting a signal through the antigen-receptor. Co-receptors appear to modulate the signaling threshold for B cell tolerance distinctly from that for B cell activation.

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